Current Issue : January - March Volume : 2021 Issue Number : 1 Articles : 5 Articles
Background: Systemic inflammatory response is closely related to the development and prognosis of liver failure.\nThis study aimed to establish a new model combing the inflammatory markers including neutrophil/lymphocyte\nratio (NLR) and red blood cell distribution width (RDW) with several hematological testing indicators to assess the\nprognosis of patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF).\nMethods: A derivation cohort with 421 patients and a validation cohort with 156 patients were recruited from\nthree hospitals. Retrospectively collecting their clinical data and laboratory testing indicators. Medcalc-15.10\nsoftware was employed for data analyses............................
Background: Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common\ngastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their\nevidence is contradictory. Therefore, the present study was conducted to investigate the epidemiology of GERD in\nIran.\nMethods: The entire steps of this systematic review and meta-analysis were based on the MOOSE protocol, and\nthe results were reported accordance with the PRISMA guideline. This review is registered on PROSPERO\n(registration number: CRD42020142861). To find potentially relevant published articles, comprehensive search was\ndone on international online databases Scopus, Science Direct, EMBASE, PubMed/Medline, CINAHL, EBSCO,.......................................
Background: We examined how extra-hepatic comorbidity burden impacts mortality in patients with cirrhosis\nreferred for liver transplantation (LT).\nMethods: Adults with cirrhosis evaluated for their first LT in 2012 were followed through their clinical course with\nlast follow up in 2019. Extra-hepatic comorbidity burden was measured using the Charlson Comorbidity Index (CCI).\nThe endpoints were 90-day transplant free survival (Cox-Proportional Hazard regression), and overall mortality\n(competing risk analysis)............................................
Background: There are only 6 cases of intraductal papillary mucinous neoplasm (IPMN) complicated with\nintraductal hemorrhage have been reported in English literatures. All these 6 cases of IPMN occurred in the old\npeople. The present rare case of IPMN complicated with intraductal hemorrhage occurred in a young woman, and\nmimicked a cystic solid pseudo-papillary neoplasm (SPN) on preoperative imaging findings.\nCase presentation: A 29-year-old young woman complained of a sustained mild right upper quadrant abdominal\npain. CT and MRI showed a lobulated, partly ill-defined cystic lesion located in the pancreatic head. Spotted\ncalcification within cystic wall was seen on CT. The lesion was demonstrated as predominantly homogeneous\nhyperattenuation on CT and homogeneous high signal without decreased signal on fat suppression sequence on\nT1WI. After contrast administration, the cystic wall and septa of lesion was showed gradually mild to moderate degree\nof enhancement over time both on CT and MRI. No communication between lesion and the main duct was found on\nMRCP and the main pancreatic duct and common bile duct were not dilated. Considering patientâ??s age, gender and\nmanifestations of lesion on CT and MRI (calcification, bleeding and gradually enhanced pattern), the present case\nmimicked as a cystic SPN. The lesion was pathologically confirmed a branch type IPMN after surgical resection.\nConclusion: We propose that IPMN may need to be taken into account in the differential diagnosis when pancreatic\ncystic lesions occur in young women with bleeding, calcification, progressive enhancement of cystic wall and no\ncommunication with the main pancreatic duct....
Background: Cirrhosis, an ineluctable development of chronic liver disease,\nstill has high mortality throughout the world despite many advances in physiopathology\nand therapy. This high mortality is closely related to the unpredictable\ncourse of cirrhosis with numerous complications. Objective: To\nevaluate the predictive factors of death during cirrhosis. Materials and methods:\nThis is an observational, descriptive study on cirrhotic patients hospitalized\nin the hepatology unit of the Center Hospitalier Universitaire in\nBouake (Ivory Coast) during the period from January 01, 2018 to December\n31, 2019. The study focused on the data collected in the medical files (paper\nformat) of hospitalized cirrhotics and the death register of the service. The\ndiagnosis of cirrhosis and the death of the cirrhotic were the main criteria for\njudgment. The secondary criteria defined were: history of cirrhosis, reasons\nfor consultation, clinical signs, biological signs, complications of cirrhosis and\nthe treatment received. The relationship between the parameters was expressed\nas an odds ratio (OR) with a 95% confidence interval (CI) and the\nsignificance threshold fixed at....................................
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